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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1996 1
1997 2
1998 1
1999 6
2000 2
2001 4
2002 6
2003 5
2004 5
2005 10
2006 10
2007 5
2008 8
2009 7
2010 5
2011 5
2012 1
2013 3
2014 7
2015 5
2016 4
2017 1
2018 3
2019 7
2020 2
2021 5
2022 11
2023 5
2024 1

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127 results

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Page 1
Relationship between PPP1R15A gene polymorphism (rs611251) and Epstein-Barr virus-associated tumors.
Song Y, Liu S, Zhao Z, Zhang Y, Yang Y, Luo B. Song Y, et al. Acta Virol. 2017;61(4):445-452. doi: 10.4149/av_2017_407. Acta Virol. 2017. PMID: 29186961
Our study explores the relationship between PPP1R15A gene polymorphism (rs611251) and Epstein-Barr virus-associated tumors for the first time. PPP1R15A gene SNP (rs611251) have association with multiple tumor types, which may provide some new clues to …
Our study explores the relationship between PPP1R15A gene polymorphism (rs611251) and Epstein-Barr virus-associated tumors for …
A PERK-Specific Inhibitor Blocks Metastatic Progression by Limiting Integrated Stress Response-Dependent Survival of Quiescent Cancer Cells.
Calvo V, Zheng W, Adam-Artigues A, Staschke KA, Huang X, Cheung JF, Nobre AR, Fujisawa S, Liu D, Fumagalli M, Surguladze D, Stokes ME, Nowacek A, Mulvihill M, Farias EF, Aguirre-Ghiso JA. Calvo V, et al. Clin Cancer Res. 2023 Dec 15;29(24):5155-5172. doi: 10.1158/1078-0432.CCR-23-1427. Clin Cancer Res. 2023. PMID: 37982738
HC4 blocked expansion of established micro-metastasis that contained ISRhigh slow-cycling cells. Single-cell gene expression profiling and imaging revealed that a significant proportion of solitary DCCs in lungs were indeed dormant and displayed an unresolved ER stress as …
HC4 blocked expansion of established micro-metastasis that contained ISRhigh slow-cycling cells. Single-cell gene expression profilin …
Protocol for PPP1R15A-inhibited mouse model establishment with subcutaneous B16F1 tumor and single-cell analysis.
Wang R, Wang M, Pei S, Zhang Y, Guo S, Guo W, Wu Z, Wang H, Li Y, Zhu Y, Meng LH, Lang J, Jin G, Xiao Y, Hu L, Kong X. Wang R, et al. STAR Protoc. 2023 Dec 15;4(4):102616. doi: 10.1016/j.xpro.2023.102616. Epub 2023 Sep 26. STAR Protoc. 2023. PMID: 37756156 Free PMC article.
Here, we present a protocol for exploring the effects of PPP1R15A inhibitor, Sephin1, on antitumor immunity of B16F1 subcutaneous tumor in mice. We describe steps for constructing single-cell transcriptome and TCR libraries, sequencing, and using sequencing data for the in …
Here, we present a protocol for exploring the effects of PPP1R15A inhibitor, Sephin1, on antitumor immunity of B16F1 subcutaneous tum …
Prognosis-related autophagy genes in female lung adenocarcinoma.
Liu Z, Zhang K, Zhao Z, Qin Z, Tang H. Liu Z, et al. Medicine (Baltimore). 2022 Jan 7;101(1):e28500. doi: 10.1097/MD.0000000000028500. Medicine (Baltimore). 2022. PMID: 35029906 Free PMC article.
Twelve down-regulated genes: NRG3, DLC1, NLRC4, DAPK2, HSPB8, PPP1R15A, FOS, NRG1, PRKCQ, GRID1, MAP1LC3C, GABARAPL1. ...Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis showed that these genes were significantly associated wit …
Twelve down-regulated genes: NRG3, DLC1, NLRC4, DAPK2, HSPB8, PPP1R15A, FOS, NRG1, PRKCQ, GRID1, MAP1LC3C, GABARAPL1. ...Ge …
Targeting Super-Enhancer-Driven Oncogenic Transcription by CDK7 Inhibition in Anaplastic Thyroid Carcinoma.
Cao X, Dang L, Zheng X, Lu Y, Lu Y, Ji R, Zhang T, Ruan X, Zhi J, Hou X, Yi X, Li MJ, Gu T, Gao M, Zhang L, Chen Y. Cao X, et al. Thyroid. 2019 Jun;29(6):809-823. doi: 10.1089/thy.2018.0550. Epub 2019 May 3. Thyroid. 2019. PMID: 30924726
Integrative analysis of RNA sequencing, chromatin immunoprecipitation sequencing, and CRISPR/Cas9-mediated gene editing was used to identify THZ1 target genes. Drug combination analysis was performed to assess drug synergy. ...Combining this integrative analysis wit …
Integrative analysis of RNA sequencing, chromatin immunoprecipitation sequencing, and CRISPR/Cas9-mediated gene editing was used to i …
The regulatory protein GADD34 inhibits TRAIL-induced apoptosis via TRAF6/ERK-dependent stabilization of myeloid cell leukemia 1 in liver cancer cells.
Song P, Yang S, Hua H, Zhang H, Kong Q, Wang J, Luo T, Jiang Y. Song P, et al. J Biol Chem. 2019 Apr 12;294(15):5945-5955. doi: 10.1074/jbc.RA118.006029. Epub 2019 Feb 19. J Biol Chem. 2019. PMID: 30782845 Free PMC article.
GADD34 (growth arrest and DNA damage-inducible gene 34) plays a critical role in responses to DNA damage and endoplasmic reticulum stress. ...We found that GADD34 knockdown decreased MCL-1 levels and that GADD34 overexpression up-regulated MCL-1 expres …
GADD34 (growth arrest and DNA damage-inducible gene 34) plays a critical role in responses to DNA damage and endoplasmic retic …
A novel TCGA-validated programmed cell-death-related signature of ovarian cancer.
Cai X, Lin J, Liu L, Zheng J, Liu Q, Ji L, Sun Y. Cai X, et al. BMC Cancer. 2024 Apr 23;24(1):515. doi: 10.1186/s12885-024-12245-2. BMC Cancer. 2024. PMID: 38654239 Free PMC article.
RESULTS: A ten-PCD-related gene signature including protein phosphatase 1 regulatory subunit 15 A (PPP1R15A), 8-oxoguanine-DNA glycosylase (OGG1), HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 (HERC1), Caspase-2....Finally, qRT-PCR confi …
RESULTS: A ten-PCD-related gene signature including protein phosphatase 1 regulatory subunit 15 A (PPP1R15A), 8-oxoguanine-DNA …
Mxi1 participates in the progression of lung cancer via the microRNA-300/KLF9/GADD34 Axis.
Lei Y, Huang Y, Lin J, Sun S, Che K, Shen J, Liao J, Chen Y, Chen K, Lin Z, Lin X. Lei Y, et al. Cell Death Dis. 2022 May 2;13(5):425. doi: 10.1038/s41419-022-04778-w. Cell Death Dis. 2022. PMID: 35501353 Free PMC article.
Mxi1 inhibited miR-300 by suppressing its transcription. miR-300 suppressed the expression of KLF9, and KLF9 negatively regulated GADD34 expression in lung cancer cells. Mxi1 or KLF9 elevation or miR-300 repression inhibited lung cancer cell proliferation, as evidenced by …
Mxi1 inhibited miR-300 by suppressing its transcription. miR-300 suppressed the expression of KLF9, and KLF9 negatively regulated GADD34 …
Transcriptional and metabolic remodeling in clear cell renal cell carcinoma caused by ATF4 activation and the integrated stress response (ISR).
van der Mijn JC, Chen Q, Laursen KB, Khani F, Wang X, Dorsaint P, Sboner A, Gross SS, Nanus DM, Gudas LJ. van der Mijn JC, et al. Mol Carcinog. 2022 Sep;61(9):851-864. doi: 10.1002/mc.23437. Epub 2022 Jun 21. Mol Carcinog. 2022. PMID: 35726553 Free PMC article.

Analysis of variance, the two-sided Student's t test, and gene set enrichment analysis were used (p < 0.05) to determine statistical significance. ...Activation of ATF4 is concomitant with enrichment of the ATF4 gene set and elevated expression of ATF4 target

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Analysis of variance, the two-sided Student's t test, and gene set enrichment analysis were used (p < 0.05) to determine statistic

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Genetic Markers of the Host to Predict the Efficacy of Colorectal Cancer Targeted Therapy.
De Mattia E, Bignucolo A, Toffoli G, Cecchin E. De Mattia E, et al. Curr Med Chem. 2020;27(25):4249-4273. doi: 10.2174/0929867326666190712151417. Curr Med Chem. 2020. PMID: 31298142 Review.
Inherent variations in KRAS 3'UTR region as well as EGF/ EGFR genes were investigated as markers of cetuximab effectiveness. More recently interesting data in the field of anti- EGFR agents were generated also for germ-line variants in genes involved in inflammation …
Inherent variations in KRAS 3'UTR region as well as EGF/ EGFR genes were investigated as markers of cetuximab effectiveness. More rec …
127 results